They can turn some genes off or on at some point. It is an external modification of DNA. Epigenetics, are traits that are above all the genes. It does not affect the sequence of the DNA, but it does how the DNA reads. It may live in the body of a person for as long as some cells are still alive. In others, it lasts in their life time from childhood to adulthood. It may also be passed over generations.
When DNA methylation is added to a methyl group or a chemical cap, it may cause some alteration to the genetic material. It alters the physical structure of the DNA but never the sequence. This can actually lead to the suppression of some genes. This means that those genes will not have the chance to be expressed. The structure will be the same, but the physical appearance will be different.
Histone is a protein that DNA wraps itself round. This allows DNA to fit into all the cells. Without it, DNA would be very long and would not be able to fit anywhere. The DNA is also required not to wrap itself too tightly on to the histone otherwise the readability will be a challenge. There are modifications that relax the histone and make the readability easier.
One may wonder, how come all the different body cells contain the same DNA but the cells are completely different. This is because the genes in every part of the body like the skin, the brain and others the genes are expressed differently. This is why the cells in all the body parts are always going to appear different.
Epigenetics can be passed on to different generations, but this is not always the case. They may be in the egg cell, the sperm cell or in both. Once the egg and sperm fuse, they may undergo a process known as reprogramming. This is when all the previous genes are erased, and the fetus is formed. The fetus can then start from scratch forming its own epigenetics.
This is however not always the case. Some of this genetics are resistant to the reprogramming process. This means that that genetics is going to be passed on to the child once the egg is fertilized. This means like factors such as food ingested before the conception of the child, may actually affect the future of the child. It is however yet to be proven in human beings.
Scientists believe that epigenetics can play a role in some cancers. Some genes might lack the ability to control how big a cell grows. These are what turn out to be tumors. These are because the body has no control over how large the cell becomes and it grows so large and makes some of the body functions quite difficult to be undertaken.
There are cells whose job is to reconstruct damaged DNA. Some epigenetics may cause this to be impossible. This means that DNA will be damaged continually with no way of getting repaired. This is one of the ways of letting cancer out.
When DNA methylation is added to a methyl group or a chemical cap, it may cause some alteration to the genetic material. It alters the physical structure of the DNA but never the sequence. This can actually lead to the suppression of some genes. This means that those genes will not have the chance to be expressed. The structure will be the same, but the physical appearance will be different.
Histone is a protein that DNA wraps itself round. This allows DNA to fit into all the cells. Without it, DNA would be very long and would not be able to fit anywhere. The DNA is also required not to wrap itself too tightly on to the histone otherwise the readability will be a challenge. There are modifications that relax the histone and make the readability easier.
One may wonder, how come all the different body cells contain the same DNA but the cells are completely different. This is because the genes in every part of the body like the skin, the brain and others the genes are expressed differently. This is why the cells in all the body parts are always going to appear different.
Epigenetics can be passed on to different generations, but this is not always the case. They may be in the egg cell, the sperm cell or in both. Once the egg and sperm fuse, they may undergo a process known as reprogramming. This is when all the previous genes are erased, and the fetus is formed. The fetus can then start from scratch forming its own epigenetics.
This is however not always the case. Some of this genetics are resistant to the reprogramming process. This means that that genetics is going to be passed on to the child once the egg is fertilized. This means like factors such as food ingested before the conception of the child, may actually affect the future of the child. It is however yet to be proven in human beings.
Scientists believe that epigenetics can play a role in some cancers. Some genes might lack the ability to control how big a cell grows. These are what turn out to be tumors. These are because the body has no control over how large the cell becomes and it grows so large and makes some of the body functions quite difficult to be undertaken.
There are cells whose job is to reconstruct damaged DNA. Some epigenetics may cause this to be impossible. This means that DNA will be damaged continually with no way of getting repaired. This is one of the ways of letting cancer out.
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